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Stereocontrolled preparation of substituted oxazolidin-2-one scaffold as the chiral building block for the synthesis of FTY720 analogues

Institute of Chemical Sciences, Department of Organic Chemistry, P. J. Šafárik University, Moyzesova 11, Košice, Slovak Republic; * Author to whom correspondence should be addressed.
(This article belongs to the section A. General Organic Synthesis)
Cite this paper as: Pomikalová, K.; Martinková, M.; Gonda, J. Stereocontrolled preparation of substituted oxazolidin-2-one scaffold as the chiral building block for the synthesis of FTY720 analogues. In Proceedings of the 13th Int. Electron. Conf. Synth. Org. Chem., 1-30 November 2009; Sciforum Electronic Conferences Series, 2009, a019.
Abstract: An efficient strereocontrolled synthesis of substituted oxazolidin-2-one synthon 11 as the key intermediate in the synthesis of FTY720 analogues starting from the highly functionalized furanose scaffold 21 is reported.

 

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