Coumarin-Chalcone Hybrids as new scaffolds in drug discovery

Conference Menu

ECSOC-13 | General Organic Synthesis

Rate this paper

13th Int. Electron. Conf. Synth. Org. Chem. 2009, a032:1-5

Communication

Download PDF (162 KB)

Coumarin-Chalcone Hybrids as new scaffolds in drug discovery

Saleta Vázquez Rodríguez*

, Silvia Serra, Lourdes Santana and Eugenio Uriarte

Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782, Spain; * Author to whom correspondence should be addressed.

(This article belongs to the section A. General Organic Synthesis)

Cite this paper as: Vázquez Rodríguez, S.; Serra, S.; Santana, L.; Uriarte, E. Coumarin-Chalcone Hybrids as new scaffolds in drug discovery. In Proceedings of the 13th Int. Electron. Conf. Synth. Org. Chem., 1-30 November 2009; Sciforum Electronic Conferences Series, 2009, a032:1-5.

Abstract: The first hydroxilated series of coumarin-chalcone derivatives has been synthesize starting from the corresponding salicyl aldehyde and β-ketoester precursors by a Knoevenagel reaction in order to obtain the methoxy derivatives which have been further hydrolyzed with a Lewis acid.

Keywords: Coumarin, Chalcone, Knoevenagel

Download PDF File (162 KB)

No comments have been added yet.

Views: 452
Rating: 0 (votes: 0)
Comments: 0

E-Mail
Password

	Reset password
	Register