Surprise in the Lithium Hydroxide Hydrolysis of a NXO-Compound

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ECSOC-13 | Bioorganic Chemistry and Natural Products

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13th Int. Electron. Conf. Synth. Org. Chem. 2009, c013:1-5

Communication

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Surprise in the Lithium Hydroxide Hydrolysis of a NXO-Compound

A. Khan Farhan, Jaywant Phopase and Ulrich Jordis*

Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9/163 1060 Vienna, Austria; * Author to whom correspondence should be addressed.

(This article belongs to the section C. Bioorganic Chemistry and Natural Products)

Cite this paper as: Khan Farhan, A.; Phopase, J.; Jordis, U. Surprise in the Lithium Hydroxide Hydrolysis of a NXO-Compound. In Proceedings of the 13th Int. Electron. Conf. Synth. Org. Chem., 1-30 November 2009; Sciforum Electronic Conferences Series, 2009, c013:1-5.

Abstract: This paper describes the unexpected outcome of the lithium hydroxide hydrolysis of the NXO-compound Boc-NPheO-OMe (1) and an independent synthesis of the product thus obtained, as well as the synthesis of 1,2,5 triazine-3,4,7- trione from 1. We submit these results for discussion to ECSOC 13 and hope to receive constructive comments and suggestions.

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