An efficient synthesis of 4H-chromenes and 4H-pyrans derivatives via an ultrasound assisted one pot three-component reaction

Bagher Kazemi; Shahrzad Javanshir

doi:10.3390/ecsoc-15-00764

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Facile Synthesis of 1,1-Diacetates Catalyzed by MCM-41-SO3H Under Solvent-free Condition

An efficient synthesis of 4H-chromenes and 4H-pyrans derivatives via an ultrasound assisted one pot three-component reaction

Bagher Kazemi

Shahrzad Javanshir

¹ Iran university of science and technology

Published: 01 November 2011 by MDPI in The 15th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-15-00764

Abstract: In this research, a new series of substituted 4H- pyrans and 4H-chromenes derivatives has been synthesized at ambient temperature in the presence of catalytic amount of sodium carbonate (20 mol %) via one-pot three-component cyclocondensation reactions of malononitrile, dialkylacetylenedicarboxylates and 1,3-diketones in ethanol under ultrasound irradiation. The synergistic effect of MCRs and ultrasound has been successfully demonstrated to offer an easy way for the synthesis of these compounds in excellent yields.

Keywords: 2-amino-4H-chromenes, 2-amino-4H-pyrans, ultrasound assisted, one pot, three-component

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Bagher Kazemi

Shahrzad Javanshir